Palletoori Monagaadu is action drama based movie in which, the movie opens with murder of a Doctor who tries to setup his medical practice in a village.Everyone knows that the Zamindar of that village is behind that murder.He doesn't like the villagers to get exposed to better things, as he fears they might get out of his control.Enters Dr.Santhi (Radhika), who is determined to complete her father's incomplete dream.She meets chiru, who will be very helpful and co-coperative to her. But, zamindar has his own cruel intentions. He plans to kills Dr.santi also, but chiru saves her.Every attempt on her life is foiled by chiru and in the end chiru manages to help Dr.santi to run her practice smoothly by bringing zamindar to justice.